Jump to Recipe Print RecipeAs the rich aroma of Slow Cooker Mississippi Pot Roast wafted through my kitchen, it felt as though I’d been transported to a cozy Southern kitchen, where the days are slow and the meals are meant to be shared. This tender, hearty dish is a lifesaver for busy weeknights, requiring minimal effort while delivering maximum comfort. Best of all, it’s perfect for meal prep; just set it and forget it until the fall-apart, juicy magic is ready. With a delightful tang from the peperoncini peppers, this pot roast not only satisfies your hunger but also warms your soul. Are you ready to indulge in a meal that will make your family gather around the table again? Let’s dive into this unforgettable recipe! What makes this pot roast unforgettable? Tenderness and Flavor: Slow Cooker Mississippi Pot Roast results in perfectly fork-tender beef infused with a robust mix of savory spices and tangy peppers. Effortless Cooking: Simply set your slow cooker and enjoy. This dish is designed for busy lives, allowing for a hands-free cooking experience. Meal Prep Superstar: Ideal for leftovers, you can easily prepare meals for the week ahead. Pair with Instant Pot mashed potatoes or serve it over rice for a hearty meal. Customizable: From spice levels to broth alternatives, this recipe welcomes creativity. Adjust ingredients based on your preferences while maintaining deliciousness. Crowd-Pleaser: No one can resist this savory goodness! Impress family and friends alike with a comforting feast that brings everyone together. Slow Cooker Mississippi Pot Roast Ingredients • For the Roast Beef Chuck Roast (2 ½ to 3 lbs) – The main protein source; look for a high-quality cut for the best flavor and tenderness. Butter (2 tablespoons) – Adds richness and helps meld flavors; substitute with dairy-free butter for a lactose-free option. • For the Seasoning Garlic Powder (1 teaspoon) – Provides essential savory depth; no substitutions are recommended. Onion Powder (1 teaspoon) – Enhances the overall flavor; no substitutions are recommended. Fine Salt (1 teaspoon) – Essential for seasoning the meat; adjust to taste if desired. Dried Parsley (1 teaspoon) – Adds mild herbal notes; fresh parsley can be used if available. Dried Dill (1 teaspoon) – Introduces a unique, tangy flavor profile; fresh dill can be substituted if desired. • For Moisture and Flavor Beef Broth (1 cup) – Provides moisture to the cooking process; chicken broth or vegetable broth can be used as alternatives. Coconut Aminos (3 tablespoons) – A soy sauce alternative that adds a slightly sweet flavor; substitute with soy sauce if avoiding soy. Peperoncini Juice (¼ cup) – Adds acidity and tang; extra peperoncini can be added for increased heat. Jarred Whole Peperoncinis (12) – Provides heat and flavor; banana peppers can be swapped if needed. Enjoy creating your Slow Cooker Mississippi Pot Roast with these delightful ingredients! Step‑by‑Step Instructions for Slow Cooker Mississippi Pot Roast Step 1: Prepare the Roast Start by patting your beef chuck roast dry with paper towels to remove any moisture. This enhances browning and flavor. Place the roast directly in the slow cooker, ensuring it fits snugly. This pressure will help the meat become tender as it cooks. Step 2: Mix the Seasoning In a small bowl, combine the softened butter, garlic powder, onion powder, fine salt, dried parsley, and dried dill. Mix them well until you have a smooth, flavorful paste. Spread this mixture evenly over the surface of the roast, allowing the spices to penetrate the meat, enriching your Slow Cooker Mississippi Pot Roast. Step 3: Add the Liquids and Peppers Pour the beef broth, coconut aminos, and peperoncini juice around the roast in the slow cooker. This liquid is essential for moisture, helping the meat become fork-tender. Next, scatter the jarred whole peperoncinis on top of the roast to infuse it with their tangy flavor as it cooks. Step 4: Set the Slow Cooker Cover the slow cooker with its lid and set it on low for 8-10 hours or high for 4-6 hours. Cooking on low allows the collagen in the beef to break down, ensuring fantastic tenderness. You’ll know it’s ready when the roast shreds effortlessly with a fork, revealing juicy pieces of beef. Step 5: Shred and Serve Once the cooking time is up, carefully remove the roast from the slow cooker and place it on a cutting board. Use two forks to shred the meat into bite-sized pieces. Return the shredded beef to the slow cooker and mix it with the flavorful juices. This final step ensures every bite of your Slow Cooker Mississippi Pot Roast is full of succulent flavor. What to Serve with Slow Cooker Mississippi Pot Roast As your rich and savory pot roast simmers away, envision the delightful accompaniments that can complete this heartwarming meal. Creamy Mashed Potatoes: The fluffy texture of mashed potatoes elevates this dish, soaking up the flavorful juices for a comforting touch. Heaven on a plate, you’ll find every forkful becomes an adventure of savory goodness. Steamed Green Beans: Bright and fresh, green beans add a crisp contrast to the tender meat while bringing vibrant color to your plate. Toss them in a little olive oil and sea salt for vibrant flavor! Garlic Bread: The aroma of warm, buttery garlic bread is irresistible; it’s perfect for scooping up that delicious sauce. A classic choice that adds an Italian twist to your Southern feast! Cauliflower Rice: A lighter, grain-free alternative, cauliflower rice complements the rich flavors of the roast without overpowering it. Plus, it brings a modern touch, allowing the pot roast to shine. Pickled Vegetables: The tanginess of pickled veggies cuts through the richness of the roast, adding a zesty element that brightens the palate. This unexpected pairing will leave a lasting impression on your guests. Red Wine: A glass of full-bodied red wine enhances the flavors of the pot roast beautifully, making every sip a delightful experience. The warmth of the wine mirrors the cozy atmosphere of your meal, perfect for sharing with loved ones. Chocolate Cake: For dessert, indulge in a rich chocolate cake that balances the savory with something sweet, rounding out your meal. The moist, dense texture plays off the flavors of the pot roast, making it a meal to remember! How to Store and Freeze Slow Cooker Mississippi Pot Roast Fridge: Cool leftovers to room temperature and store in an airtight container for up to 5 days. Ensure it’s well-sealed to maintain freshness and flavor. Freezer: For longer storage, freeze your Mississippi Pot Roast in a freezer-safe container for up to 3 months. Thaw overnight in the fridge when ready to enjoy again. Reheating: To reheat, gently warm the shredded meat in a saucepan on low heat or in the microwave. Add a splash of beef broth or pan juices to keep it moist and flavorful. Portioning: Consider portioning your Slow Cooker Mississippi Pot Roast into individual servings before freezing, making meal prep a breeze for busy days. Make Ahead Options These Slow Cooker Mississippi Pot Roast preparations are perfect for busy home cooks looking to save time! You can season and prepare the beef chuck roast up to 24 hours in advance by mixing the butter and spices and applying them directly to the meat. Just wrap it tightly in plastic wrap and refrigerate. The liquid ingredients, like beef broth and peperoncini juice, can also be pre-measured and stored separately in the fridge. For the greatest quality, avoid adding the broth until you’re ready to cook. When you’re ready to serve, simply place the roast in the slow cooker with the reserved broth and whole pepperoncini, then set and forget. Your family will enjoy the same tender, flavorful results with minimal effort! Slow Cooker Mississippi Pot Roast Variations Feel free to make this beloved dish your own by exploring delightful substitutions and creative twists! Dairy-Free: Substitute butter with a plant-based option, ensuring the same rich flavor without dairy. Soy Sauce Alternative: Use soy sauce in place of coconut aminos for a bolder, umami punch if you’re okay with soy. Herb Infusion: Add fresh herbs like rosemary or thyme for an aromatic twist that elevates the overall flavor profile. Spicy Kick: Increase heat by adding sliced jalapeños alongside the peperoncinis for a zesty surprise. BBQ Flair: Incorporate your favorite barbecue sauce instead of beef broth for a smoky, sweet flavor that’s simply irresistible. Veggie Boost: Toss in diced carrots or potatoes during cooking to create a hearty one-pot meal that satisfies. Seasoned Variations: Consider sprinkling taco seasoning for a Mexican-inspired flair—you’ll be surprised how well those flavors work together! Gluten-Free: To keep it gluten-free, ensure your broth and any substitutes are certified gluten-free, especially if using soy sauce. With each of these variations, you’ll transform your Slow Cooker Mississippi Pot Roast into something uniquely yours—perfect for cozy family dinners or meal prepping delicious leftovers! Expert Tips for Slow Cooker Mississippi Pot Roast Choose Quality Beef: Select a high-quality beef chuck roast for the best flavor and tenderness. Avoid tough cuts that won’t break down properly in the slow cooker. Low and Slow: Always cook on low for the best results. This method allows the collagen to break down, ensuring a tender and juicy pot roast. Avoid Excess Liquid: Don’t add too much liquid to the slow cooker. The roast will release its own juices, and too much liquid can make the dish watery. Season Generously: Don’t skimp on the seasoning blend. The garlic and onion powder are essential for flavor depth, making every bite of your Slow Cooker Mississippi Pot Roast a delight. Shred Thoroughly: For maximum flavor, shred the meat and mix it back into the juices before serving. This ensures that every piece of beef is coated in the delicious sauce. Experiment Boldly: Feel free to adjust spice levels by adding more or fewer peperoncinis if you crave more heat. This dish is flexible, inviting your creative touch! Slow Cooker Mississippi Pot Roast Recipe FAQs What type of beef should I use for the pot roast? Absolutely! I recommend using a beef chuck roast between 2 ½ to 3 lbs for optimal tenderness and flavor. Look for a high-quality cut that has good marbling; it helps break down during cooking, ensuring a juicy and fork-tender result. How should I store leftovers from my Mississippi Pot Roast? Cool your leftovers to room temperature and store them in an airtight container in the fridge for up to 5 days. Make sure it’s sealed well to maintain freshness and flavor, and you can enjoy the rich goodness again for your next meal! Can I freeze the Slow Cooker Mississippi Pot Roast? Very much so! To freeze, allow the pot roast to cool completely, then transfer it to a freezer-safe container. It will keep well for up to 3 months. To reheat, thaw it overnight in the fridge, and then warm it in a saucepan on low heat, adding a splash of beef broth or pan juices to keep it moist. What if the roast turns out tough after cooking? Don’t worry! If your pot roast isn’t as tender as you hoped, it may need more time to cook. Try returning it to the slow cooker on low for another hour or two. This longer cooking time allows the collagen in the meat to break down further, resulting in that desired fork-tender texture. Are there any specific dietary considerations? Certainly! This Slow Cooker Mississippi Pot Roast can be made dairy-free by substituting regular butter with a plant-based butter alternative. Also, if you have soy sensitivities, you can replace coconut aminos with soy sauce. Always check ingredient labels for potential allergens if you’re serving guests with specific dietary restrictions. How spicy is the Slow Cooker Mississippi Pot Roast? It’s adjustable! The level of spice mainly comes from the peperoncinis. If you’re concerned about the heat, you can use fewer peppers or choose milder banana peppers instead. For the brave, adding extra peperoncinis will ramp up the flavor and heat, making it a delightful experience for spice lovers. Slow Cooker Mississippi Pot Roast: The Ultimate Comfort Dish No ratings yet Slow Cooker Mississippi Pot Roast is a tender and flavorful dish perfect for busy weeknights, requiring minimal effort. Print Recipe Pin Recipe Prep Time 15 minutes minsCook Time 10 hours hrsTotal Time 10 hours hrs 15 minutes mins Servings: 6 servingsCourse: DinnerCuisine: SouthernCalories: 350 Ingredients Equipment Method Nutrition Notes Ingredients 1x2x3x? For the Roast2.5 to 3 lbs Beef Chuck Roast High-quality cut for best flavor and tenderness.2 tablespoons Butter Substitute with dairy-free butter for lactose-free option.For the Seasoning1 teaspoon Garlic Powder Essential savory depth; no substitutions recommended.1 teaspoon Onion Powder Enhances overall flavor; no substitutions recommended.1 teaspoon Fine Salt Essential for seasoning; adjust to taste.1 teaspoon Dried Parsley Adds mild herbal notes; fresh parsley can be used.1 teaspoon Dried Dill Introduces a unique flavor profile; fresh dill can be substituted.For Moisture and Flavor1 cup Beef Broth Can substitute with chicken or vegetable broth.3 tablespoons Coconut Aminos Soy sauce alternative; substitute with soy sauce if needed.0.25 cup Peperoncini Juice Adds acidity and tang; extra peperoncini can be added.12 pieces Jarred Whole Peperoncinis Provides heat and flavor; banana peppers can be swapped. Equipment slow cooker Method Step-by-Step InstructionsPat the beef chuck roast dry with paper towels and place directly in the slow cooker.In a bowl, combine softened butter, garlic powder, onion powder, fine salt, dried parsley, and dried dill to make a paste. Spread over the roast.Pour beef broth, coconut aminos, and peperoncini juice around the roast. Scatter jarred whole peperoncinis on top.Cover the slow cooker and set on low for 8-10 hours or high for 4-6 hours.After cooking, remove the roast, shred it using two forks, and return it to the juices in the slow cooker. Nutrition Serving: 1servingCalories: 350kcalCarbohydrates: 5gProtein: 36gFat: 20gSaturated Fat: 10gPolyunsaturated Fat: 1gMonounsaturated Fat: 4gCholesterol: 100mgSodium: 800mgPotassium: 800mgFiber: 1gSugar: 1gCalcium: 2mgIron: 15mg NotesChoose a high-quality beef chuck roast and avoid excess liquid to prevent the dish from becoming watery. Mix the shredded beef back into the juices for maximum flavor. 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